[Moslosooflavone ameliorates dextran sulfate sodium-induced colitis in mice by suppressing intestinal epithelium apoptosis <i>via</i> inhibiting the PI3K/AKT signaling pathway].
MOS alleviates experimental colitis in mice by inhibiting intestinal epithelial apoptosis via inhibiting the PI3K/AKT pathway, thereby restoring intestinal barrier integrity and reducing inflammation.
Authors
- Lugen Zuo (ORCID: https://orcid.org/0000-0002-8300-0860)
- Xiaohua Chen (ORCID: https://orcid.org/0000-0002-5696-8315)
- Jingjing Yang (ORCID: https://orcid.org/0000-0003-2579-3919)
- Fei Chu (ORCID: https://orcid.org/0000-0001-8487-9697)
- Bowen Song (ORCID: https://orcid.org/0009-0006-6768-5990)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.04.17
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article