[High expression of CDKN3 promotes migration and invasion of gastric cancer cells by regulating the p53/NF-κB signaling pathway and inhibiting cell apoptosis].

CDKN3 is highly expressed in gastric cancer tissues and affects patient prognosis. CDKN3 overexpression promotes proliferation, invasion and migration and suppressed apoptosis of gastric cancer cells possibly through the p53/NF-κB signaling pathway.

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Publication Details

Journal
PubMed
Published
2025-04-20
DOI
https://doi.org/10.12122/j.issn.1673-4254.2025.04.21
Primary Topic
Cancer-related Molecular Pathways
Type
article
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[High expression of CDKN3 promotes migration and invasion of gastric cancer cells by regulating the p53/NF-κB signaling pathway and inhibiting cell apoptosis].

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[High expression of CDKN3 promotes migration and invasion of gastric cancer cells by regulating the p53/NF-κB signaling pathway and inhibiting cell apoptosis].

Yakui Liu, Yu Shen, Zhiqiang Wan, Ying Zhang, Tao Song, Shuanhu Wang
article en

Abstract

CDKN3 is highly expressed in gastric cancer tissues and affects patient prognosis. CDKN3 overexpression promotes proliferation, invasion and migration and suppressed apoptosis of gastric cancer cells possibly through the p53/NF-κB signaling pathway.

PubMedVol. 45(4)
Bengbu Medical College (CN), First Affiliated Hospital of Bengbu Medical College (CN)
Cancer-related Molecular Pathways
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