[<i>Zheng Gan</i> Decoction inhibits diethylnitrosamine-induced hepatocellular carcinoma in rats by activating the Hippo/YAP signaling pathway].
ZGF inhibits DEN-induced HCC in rats by activating the Hippo/YAP pathway <i>via</i> upregulating MST1 and LATS1 expression, which promotes YAP phosphorylation and degradation to suppress proliferation and induce apoptosis of the tumor cells.
Authors
- Xu Liu (ORCID: https://orcid.org/0000-0003-4664-2060)
- Tong Sun (ORCID: https://orcid.org/0000-0003-3861-8933)
- Yimin Wang (ORCID: https://orcid.org/0000-0002-2701-0714)
- Sheng Huang (ORCID: https://orcid.org/0009-0001-9298-7548)
- Tingting Song (ORCID: https://orcid.org/0000-0002-2970-0129)
- Yun Ran (ORCID: https://orcid.org/0009-0009-2478-9994)
Institutions
- Minzu University of China (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.04.15
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article