[4‑(Arylethyl)‑pyrrolo[2,3-d] pyrimidine improves post-traumatic stress disorder in mice by inhibiting mGluR5-regulated ERK1/2-SGK1 signaling pathway].
The compound 10b ameliorates PTSD-like behaviors induced by SPS in mice possibly by inhibiting mGluR5 expression to modulate the ERK1/2-SGK1 signaling pathway.
Authors
- Shaojie Yang (ORCID: https://orcid.org/0000-0001-9836-8548)
- Chao He (ORCID: https://orcid.org/0000-0002-4629-4740)
- Guoqi Zhu (ORCID: https://orcid.org/0000-0001-8157-1021)
Institutions
- Anhui Medical University (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.04.12
- Citations
- 1
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article