Bortezomib as a Potential Treatment for Recurrent Autoimmune Hepatitis Following Pediatric Liver Transplantation
This case emphasizes the effective use of bortezomib as a rescue therapy for steroid-resistant rejection and the recurrence of autoimmune hepatitis following pediatric liver transplantation. It highlights the significance of alternative therapeutic approaches in addressing complex post-transplant immune complications. Furthermore, this case prompts crucial considerations for future research, such as the monitoring of autoimmune disease reactivation and the potential role of drugs like bortezomib in managing immune-related complications after liver transplantation.
Authors
- Konstantin Semash (ORCID: https://orcid.org/0000-0001-5830-5235)
- P. M. Gadzhieva
- A. R. Monakhov (ORCID: https://orcid.org/0000-0002-3537-6601)
- Timur Dzhanbekov (ORCID: https://orcid.org/0000-0002-8857-947X)
- Mansur Nasirov (ORCID: https://orcid.org/0000-0002-1365-9125)
Institutions
- Sechenov University (RU)
- V.I.Shumakov Federal Research Center of Transplantology and Artificial Organs (RU)
- Tashkent Pediatric Medical Institute (UZ)
Publication Details
- Journal
- Pediatric Transplantation
- Published
- 2025-04-30
- DOI
- https://doi.org/10.1111/petr.70082
- Citations
- 1
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 1.32