LSM2 drives glioma progression through alternative splicing dysregulation: a multi-omics approach to identify a potential therapeutic target
Our findings demonstrate that <i>LSM2</i> plays a critical role in glioma progression through the regulation of RNA splicing dynamics. Elevated <i>LSM2</i> expression serves as a prognostic biomarker and offers promising potential as a therapeutic target in glioma.
Authors
- Chang Ge (ORCID: https://orcid.org/0000-0003-0293-4408)
- Jingxuan Xu
- Wenjie Zhang (ORCID: https://orcid.org/0000-0001-6457-7800)
- Yang Cao (ORCID: https://orcid.org/0000-0001-7787-8506)
Institutions
- Xinjiang Medical University (CN)
- Second Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.3389/fonc.2025.1521608
- Citations
- 1
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.81