Similar burden of rare genetic variants in ischemic and non-ischemic dilated cardiomyopathy
Patients with ischemic dilated cardiomyopathy undergoing heart transplant possessed a similar burden of rare disease-causing variants as those with non-ischemic dilated cardiomyopathy. Our results suggest that genetic testing may be beneficial in patients with advanced heart failure requiring heart transplant due to ischemic dilated cardiomyopathy to detect disease-causing variants in cardiomyopathy-associated genes.
Authors
- L. Czer (ORCID: https://orcid.org/0000-0001-5744-2625)
- Louie Cao (ORCID: https://orcid.org/0000-0002-9680-5801)
- Ian Williamson
- M. Kittleson (ORCID: https://orcid.org/0000-0003-4492-2691)
- Joshua A. Rushakoff (ORCID: https://orcid.org/0000-0003-1254-6687)
- Anja Karlstaedt (ORCID: https://orcid.org/0000-0001-5689-3571)
- Evan P Kransdorf
Institutions
- Cedars-Sinai Medical Center (US)
- Cedars-Sinai Smidt Heart Institute (US)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-04-29
- DOI
- https://doi.org/10.3389/fcvm.2025.1542653
- Citations
- 1
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39