Long donor leukocyte telomeres raise risk of severe COVID-19 in recipients of allogeneic hematopoietic cell transplant
These findings suggest that long donor leukocyte telomeres may trigger an excessive neutrophil response and severe COVID-19 in allogeneic HCT recipients, potentially due to a transplant-related but TL-independent weak T-cell response.
Authors
- Simon Verhulst (ORCID: https://orcid.org/0000-0002-1143-6868)
- James M. Anderson (ORCID: https://orcid.org/0000-0003-2765-7996)
- Abraham Aviv (ORCID: https://orcid.org/0000-0002-7441-0227)
- Wael Saber (ORCID: https://orcid.org/0000-0002-6544-5815)
- Kyra Jennifer Waligora Mendez
- Stephen R. Spellman (ORCID: https://orcid.org/0000-0002-7271-8252)
- Tsung-Po Lai
- Shahinaz M. Gadalla (ORCID: https://orcid.org/0000-0002-0108-2381)
Institutions
- Rutgers, The State University of New Jersey (US)
- University of Groningen (NL)
- University of Washington (US)
- Medical College of Wisconsin (US)
- National Cancer Institute (US)
- Division of Cancer Epidemiology and Genetics
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.3389/fimmu.2025.1524608
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00