Ginsenoside Rg1 controls CKLF1-mediated apoptosis to reduce hypoxic/reoxygenation injury in HT22 cells
Rg1 attenuates OGD/R injury, reduces oxidative stress and apoptosis in HT22 cells by inhibiting CKLF1 expression and alleviates the inflammatory response in activated BV-2 cells, showing therapeutic potential.
Authors
- Xuan Zhu (ORCID: https://orcid.org/0000-0002-3969-7904)
- Qidi Ai (ORCID: https://orcid.org/0000-0002-1647-2825)
- Yuchen Zhu (ORCID: https://orcid.org/0000-0001-5148-8569)
- Junpeng Long (ORCID: https://orcid.org/0000-0002-0298-7481)
- Boyu Kuang
- Shasha Liu (ORCID: https://orcid.org/0000-0002-2855-3999)
- Yantao Yang
- Qian Yan (ORCID: https://orcid.org/0009-0008-7483-0572)
- Jinping Liang
- Yan Yang (ORCID: https://orcid.org/0000-0001-7465-3811)
- Feng Li (ORCID: https://orcid.org/0000-0003-3771-3816)
- Yang Sun (ORCID: https://orcid.org/0000-0002-0156-2756)
- Yuting Lin (ORCID: https://orcid.org/0000-0003-4658-1579)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Changsha Hospital for Maternal and Child Health Care (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.3389/fphar.2025.1525605
- Citations
- 2
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.61