Association of intestinal mucosal barrier function with intestinal microbiota in Spleen-Kidney Yang Deficiency IBS-D mice
The combination of <i>Folium senna-</i>adenine administration with restraint-clamping tail can be used to successfully establish an IBS-D mouse model with Spleen-Kidney Yang Deficiency. This model leads to damage to the intestinal mucosal structure. <i>Streptococcus</i>, <i>Serratia</i>, <i>Helicobacter</i>, <i>Phocaeicola</i>, and <i>Desulfomicrobium</i> may serve as potential biological markers for the intestinal mucosal microbiota.
Authors
- Zhoujin Tan (ORCID: https://orcid.org/0000-0003-3193-073X)
- Na Deng (ORCID: https://orcid.org/0000-0002-4557-5372)
- Liwen Li (ORCID: https://orcid.org/0000-0002-5044-5388)
- Qi Long
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.3389/fmicb.2025.1567971
- Citations
- 4
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 7.24