Clinicopathological characteristics and prognostic outcomes of pregnancy-associated colorectal cancer: A 24-year experience

Patients with poorly differentiated tumors exhibited worse outcomes than those with moderately and highly differentiated tumors. Early-stage diagnosis and timely treatment significantly improved maternal survival and fetal outcomes in pregnant patients with CRC. Advanced tumor stages and delayed diagnosis were observed to be associated with poorer maternal prognoses and may require interventions that compromise fetal survival. Fetal outcomes depend on the pathological stage of the mother's cancer, the gestational age at diagnosis, and treatment strategies.

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Publication Details

Journal
World Journal of Gastroenterology
Published
2025-04-29
DOI
https://doi.org/10.3748/wjg.v31.i17.106508
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinicopathological characteristics and prognostic outcomes of pregnancy-associated colorectal cancer: A 24-year experience

Yantao Tian, Dongkui Xu, Lin Qi, Liwen Fan et al.
World Journal of Gastroenterology
Cancer Risks and Factors
article

Clinicopathological characteristics and prognostic outcomes of pregnancy-associated colorectal cancer: A 24-year experience

Yantao Tian, Dongkui Xu, Lin Qi, Liwen Fan, Chao Shang
article en

Abstract

Patients with poorly differentiated tumors exhibited worse outcomes than those with moderately and highly differentiated tumors. Early-stage diagnosis and timely treatment significantly improved maternal survival and fetal outcomes in pregnant patients with CRC. Advanced tumor stages and delayed diagnosis were observed to be associated with poorer maternal prognoses and may require interventions that compromise fetal survival. Fetal outcomes depend on the pathological stage of the mother's cancer, the gestational age at diagnosis, and treatment strategies.

World Journal of GastroenterologyVol. 31(17)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Openalex Percentile: Top 86%
Cancer Risks and Factors
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Clinicopathological characteristics and prognostic outcomes of pregnancy-associated colorectal cancer: A 24-year experience — Yantao Tian, Dongkui Xu, et al. · World Journal of Gastroenterology (2025) | TGRS Research Map | TGRS