Metabolomic and proteomic analyses of renal function after liver transplantation
This study revealed distinct metabolomic and proteomic signatures associated with renal dysfunction post-LT. Proteomic profiles indicated a delayed recovery compared to metabolomic profiles, suggesting a dynamic and muti-layered renal recovery process. Further research is warranted to elucidate the functional implications of the differential proteins and metabolites for improved monitoring and therapeutic strategies.
Authors
- Paolo Cravedi (ORCID: https://orcid.org/0000-0001-7837-0923)
- Josh Levitsky (ORCID: https://orcid.org/0000-0001-7527-6093)
- Peter Kotanko (ORCID: https://orcid.org/0000-0003-4373-412X)
- Nadja Grobe (ORCID: https://orcid.org/0000-0001-9812-7672)
- Xiaoling Wang (ORCID: https://orcid.org/0000-0002-4301-4133)
- Barbara Franchin (ORCID: https://orcid.org/0009-0009-3546-3375)
Institutions
- Northwestern University (US)
- Renal Research Institute (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Frontiers in Transplantation
- Published
- 2025-04-29
- DOI
- https://doi.org/10.3389/frtra.2025.1572852
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35