Clinicopathological characteristics and diagnostic performance of metagenomic pathogen detection technology in mycobacterial infections among HIV patients
MetaPath™ is a highly effective diagnostic tool for mycobacterial infections, particularly in tissue biopsies. HIV-positive status, lymph node involvement, and MetaPath™ positivity independently predict mycobacterial detection. HIV-positive patients exhibit distinct clinicopathological features, emphasizing the need for tailored diagnostic and therapeutic approaches based on immune status.
Authors
- Ting Liu (ORCID: https://orcid.org/0000-0003-2599-784X)
- Fei‐Fei Liu (ORCID: https://orcid.org/0000-0003-4344-6486)
- Liming Qi (ORCID: https://orcid.org/0000-0002-4960-6156)
- Hongxin Zhao (ORCID: https://orcid.org/0000-0002-1159-9069)
- Jianfeng Zhou (ORCID: https://orcid.org/0000-0003-0862-7951)
- Xingang Zhou (ORCID: https://orcid.org/0000-0003-2681-7177)
- Kun Yang
- Zhen Zhou (ORCID: https://orcid.org/0000-0003-0706-9089)
- Liang Zhang (ORCID: https://orcid.org/0000-0002-2279-2657)
- Xiao Jiang (ORCID: https://orcid.org/0000-0001-7335-4238)
- Xiaoyi Han
- Lei Sun (ORCID: https://orcid.org/0000-0002-0101-0695)
- Man Li (ORCID: https://orcid.org/0000-0002-5710-5175)
- Xiaoyou Chen
- Xiangmei Chen
- Jiamin Chen
Institutions
- Capital Medical University (CN)
- Kingmed Diagnostics (CN)
- Beijing Ditan Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.3389/fcimb.2025.1584189
- Citations
- 4
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 5.42