Regenerative capabilities of platelet-rich plasma in different age groups
In the first 24 hours, we revealed pro-oxidant stimulating effect of PRP from young donors with increase in metabolic activity and no cell necrosis. Addition of PRP from elderly donors on the first day was accompanied by lower metabolic activity of culture and higher percentage of cell necrosis and apoptosis. There was no difference in migration activity of cells depending on donor age.
Authors
- Ekaterina P. Brodovskaya (ORCID: https://orcid.org/0000-0002-1060-9843)
- Alla Polozova (ORCID: https://orcid.org/0009-0002-3029-791X)
- Елена Николаевна Коваленко (ORCID: https://orcid.org/0000-0001-6444-2172)
- Т. И. Власова (ORCID: https://orcid.org/0000-0002-2624-6450)
- K.S. Madonov (ORCID: https://orcid.org/0000-0002-3709-1458)
- S.S. Myakushin (ORCID: https://orcid.org/0000-0002-2466-7681)
- А П Власов (ORCID: https://orcid.org/0000-0003-4731-2952)
Institutions
- National Research Mordovia State University (RU)
Publication Details
- Journal
- Pirogov Russian Journal of Surgery
- Published
- 2025-04-29
- DOI
- https://doi.org/10.17116/hirurgia202505136
- Citations
- 1
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.84