A critical appraisal of the clinico-radiological, histopathological and immunohistochemical profile of CT-guided and bronchoscopy-guided biopsies in lung lesions
Integrating conventional histopathology with IHC results in accurate diagnosis, thereby avoiding a broad diagnosis of non-small-cell lung carcinoma (NSCLC). Subclassification of NSCLC has significant treatment implications, especially for advanced-stage tumours for which chemotherapy or targeted therapy is being considered. The focus should be on the judicious use of IHC based on histological type because of the limited availability of tissues in bronchoscopic and CT-guided biopsy specimens.
Authors
- Dipti Sidam
- Charu Agarwal (ORCID: https://orcid.org/0000-0002-7552-2837)
- Aniruna Dey
- Ruchi Sachdeva (ORCID: https://orcid.org/0000-0002-0431-9620)
- Varsha Chauhan (ORCID: https://orcid.org/0000-0001-6465-5733)
- Mukta Pujani (ORCID: https://orcid.org/0000-0003-3953-1864)
- Sidra Abbas (ORCID: https://orcid.org/0009-0001-0117-4390)
- Jyoti Rajpoot (ORCID: https://orcid.org/0000-0002-1232-4323)
- Minakshi Bhardwaj
Institutions
- Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (IN)
- ESIC Hospital (IN)
Publication Details
- Journal
- Lung India
- Published
- 2025-04-29
- DOI
- https://doi.org/10.4103/lungindia.lungindia_496_24
- Citations
- 1
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52