The effect of intraocular pressure during phacoemulsification in patients with either diabetic retinopathy or glaucoma; a randomized controlled feasibility trial

What is known Traditionally, phacoemulsification has been carried out under relatively high intraocular pressure (IOP) to mitigate the effects of post occlusion aspiration surge during lens removal. A new enhanced phacoemulsification fluidics system has reduced surge allowing surgeons to operate at considerably lower, and more physiological IOP levels. What is new In patients undergoing phacoemulsification for moderate cataracts with either co-existing diabetic retinopathy or glaucoma, an IOP of 30 mmHg using the Centurion active sentry system did not result in any decrease in surgical efficiency or increase in complication rates compared to a higher pressure of 60 mmHg. Lower IOP phacoemulsification caused less short-term changes in the retinal microvasculature than higher pressure, the long-term significance of which is unknown and further study is needed.

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Publication Details

Journal
Graefe s Archive for Clinical and Experimental Ophthalmology
Published
2025-04-29
DOI
https://doi.org/10.1007/s00417-025-06839-0
Citations
4
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
6.83

Funders

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article

The effect of intraocular pressure during phacoemulsification in patients with either diabetic retinopathy or glaucoma; a randomized controlled feasibility trial

Michael Quinn, Raffaele Raimondi, Tünde Pető, Karmen Sow et al.
4 citations
Graefe s Archive for Clinical and Experimental Ophthalmology
Glaucoma and retinal disorders
6.83
article

The effect of intraocular pressure during phacoemulsification in patients with either diabetic retinopathy or glaucoma; a randomized controlled feasibility trial

Michael Quinn, Raffaele Raimondi, Tünde Pető, Karmen Sow, David Steel, Nicholas Wride, Maged Habib, Alan Sproule, Alyson Muldrew
article en
4 citations

Abstract

What is known Traditionally, phacoemulsification has been carried out under relatively high intraocular pressure (IOP) to mitigate the effects of post occlusion aspiration surge during lens removal. A new enhanced phacoemulsification fluidics system has reduced surge allowing surgeons to operate at considerably lower, and more physiological IOP levels. What is new In patients undergoing phacoemulsification for moderate cataracts with either co-existing diabetic retinopathy or glaucoma, an IOP of 30 mmHg using the Centurion active sentry system did not result in any decrease in surgical efficiency or increase in complication rates compared to a higher pressure of 60 mmHg. Lower IOP phacoemulsification caused less short-term changes in the retinal microvasculature than higher pressure, the long-term significance of which is unknown and further study is needed.

Graefe s Archive for Clinical and Experimental OphthalmologyVol. 263(8)
Queen's University Belfast (GB), Sunderland Eye Infirmary (GB), Newcastle University (GB)
Boehringer Ingelheim, Bayer, Roche, Boehringer Ingelheim, Alimera Sciences, Alcon
Affordable and clean energy
Openalex Percentile: Top 3%
Glaucoma and retinal disorders
6.83
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The effect of intraocular pressure during phacoemulsification in patients with either diabetic retinopathy or glaucoma; a randomized controlled feasibility trial — Michael Quinn, Raffaele Raimondi, et al. · Graefe s Archive for Clinical and Experimental Ophthalmology (2025) | TGRS Research Map | TGRS