Naringenin Attenuates Ox-LDL-induced Injury in HUVECs by Regulating Lipophagy Partly through the SOCE Pathway
In summary, NAR can increase autophagy levels and decrease lipid accumulation in HUVECs, eventually protecting against ox-LDL-induced injury in HUVECs, which is associated with inhibition of the SOCE pathway.
Authors
- Xinyu He (ORCID: https://orcid.org/0009-0008-1290-8346)
- Yanran Chen (ORCID: https://orcid.org/0000-0002-0475-2432)
- Mengyuan Wang
- Linhong Jiang (ORCID: https://orcid.org/0000-0003-1297-8797)
- Siqi Zhu (ORCID: https://orcid.org/0000-0001-6307-1189)
- Haixia Wang (ORCID: https://orcid.org/0000-0002-5782-8242)
- Jingwei Chen (ORCID: https://orcid.org/0000-0001-5736-4807)
- Ying Xiong (ORCID: https://orcid.org/0000-0002-6215-4297)
- Jun Long (ORCID: https://orcid.org/0000-0001-9765-1579)
- Wu Yingying
- Dongping Yuan
- Dandan Bai
- Yunjun Yang
- Wenxin Wang (ORCID: https://orcid.org/0009-0007-6083-0099)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Suzhou Traditional Chinese Medicine Hospital (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-04-29
- DOI
- https://doi.org/10.2174/0113816128335261241216110529
- Citations
- 1
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China
- Nanjing University of Chinese Medicine