Urogenital Anomalies in Anorectal Malformations and Hirschsprung’s Disease: Prevalence,Diagnosis, and Management

Introduction: Urogenital anomalies are responsible of approximately 50% of end-stage renal disease in children [5]. It is important to make an early clinical diagnosis and provide prompt management of these anomalies to prevent progression to renal failure. The aim of this study was to establish the correlation between urinary pathologies and anorectal malformations and Hirschsprung's disease and present their therapeutic particularities. Means and Methods: We retrospectively conducted a descriptive study at the Pediatric Surgery Department of the Queen Fabiola Children's University Hospital (HUDERF) in Brussels. We got a clearance consent from the ethical committee of our hospital. During one month, we retrieved files of children who consulted for anorectal malformations and Hirschsprung’s diseases from August 1, 2011 to June 31, 2024. We Included all patients presenting Hirschsprung’s disease and those with upper anorectal malformations. We excluded patients who presented lower anorectal malformations. Clinical parameters that we recorded included: age, sex, type of imaging, type of urinary anomalies and treatment. Data were analyzed with Microsoft Of ice Excel 2010 and SPSS software. Results: We included 50 patients in our study; 16 cases of upper anorectal malformations and 34 cases of Hirschsprung's disease. For radiologic assessments, 30 patients underwent abdominal ultrasound (US) and urethrocys to graphy was done in 8 patients. Seven cases of urologic anomalies were associated to anorectal malformations 43.8%. The dif erent urinary abnormalities found were multicystic kidney (3 cases), vesicoureteral reflux (2 cases) and renal dysplasia (2 cases). Four cases of urologic malformations were associated to Hirschsprung's disease at least 11.8% (2 cases of megaureter and 2 cases of hydronephrosis). The conservative treatment has been practiced associated to antibiotic prophylaxis in 10 cases. Conclusion: This study is showing that urogenital abnormalities are mostly associated to anorectal malformations than Hirschsprung's disease. In many cases the treatment is conservative