HuangE Capsules Improve Bladder Function in BOO-induced Overactive Bladder Rats: Network Pharmacology and Experimental Validation
HEC could improve bladder function and morphology in BOO-induced OAB rats by reducing the expression of RhoA, ROCK1, and ROCK2 and lowering levels of oxidative stress and inflammation.
Authors
- Siyu Han (ORCID: https://orcid.org/0000-0001-8709-5564)
- Ran Zhong (ORCID: https://orcid.org/0000-0001-6840-2661)
- Haisheng Chen (ORCID: https://orcid.org/0000-0002-1383-9476)
- Heyang Liu (ORCID: https://orcid.org/0009-0007-0402-1078)
- Yuewen Pang
- Shuang He (ORCID: https://orcid.org/0000-0001-9354-7029)
- Junyao Duan
- Yongji Yan (ORCID: https://orcid.org/0000-0002-8748-4831)
- Shiyu Zhao (ORCID: https://orcid.org/0000-0003-1982-0044)
- Peizhe Li
- Jing Shi (ORCID: https://orcid.org/0000-0003-4807-9910)
- Huijie Gong
Institutions
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Combinatorial Chemistry & High Throughput Screening
- Published
- 2025-04-25
- DOI
- https://doi.org/10.2174/0113862073373430250415070358
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00