Dapagliflozin alleviates thioacetamide induced-liver fibrosis in rats via controlling the Nrf2/HO-1 and TLR4/TGF-β1/PI3K signaling pathways
Due to its interactions with the Nrf2/HO-1 and TLR4 pathways, our research showed that Dapa had antioxidant and anti-inflammatory qualities against TAA-induced liver fibrosis.
Authors
- A. Ramadan (ORCID: https://orcid.org/0000-0001-7212-3657)
- Reda M. S. Korany (ORCID: https://orcid.org/0000-0002-2169-0317)
- Naglaa M. Hassan (ORCID: https://orcid.org/0000-0002-3195-1568)
- Hany M. Fayed (ORCID: https://orcid.org/0000-0002-3673-5733)
- Gehan M. Kamel (ORCID: https://orcid.org/0000-0003-1270-9415)
Institutions
- Cairo University (EG)
- National Research Centre (EG)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1080/08923973.2025.2496661
- Citations
- 11
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 14.54