Plasminogen activator inhibitor 1 is a novel predictor in human serum/follicular fluid for diminished ovarian reserve
Our study reveals that the expression of PAI-1 is higher in serum and follicular fluid of DOR patients. And it is positively correlated with FSH, FSH/LH and negatively correlated with AMH/AFC, which is necessary to investigate the role of PAI-1 in regulating the growth and development of follicles and the pathogenesis of DOR in future.
Authors
- Xinshu Li (ORCID: https://orcid.org/0000-0002-3361-5963)
- Hua Guo
- Xue Chen (ORCID: https://orcid.org/0000-0002-4441-9159)
Institutions
- Ningxia Medical University (CN)
Publication Details
- Journal
- BMC Women s Health
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s12905-025-03710-6
- Citations
- 3
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.09
Funders
- Ningxia Medical University