Dysregulated gastric microbial communities and functional shifts in chronic atrophic versus non-atrophic gastritis: a Helicobacter pylori-Negative observational study
Gastric mucosal microbiota dysbiosis and functional shifts are significantly associated with chronic atrophic gastritis. Taxa such as Sphingomonas and Ralstonia, enriched in CAG patients, may indicate microbial signatures associated with early atrophic transition and provide candidates for further mechanistic validation.
Authors
- Jiapeng Deng (ORCID: https://orcid.org/0000-0002-0332-9296)
- Hong Yao (ORCID: https://orcid.org/0000-0002-3333-0925)
- Ling She
- Dongsong Liu (ORCID: https://orcid.org/0000-0002-1334-8466)
- Fengbin Liu (ORCID: https://orcid.org/0000-0003-2641-7499)
- Youjun Deng (ORCID: https://orcid.org/0000-0001-8508-4773)
- Tingfeng Wu (ORCID: https://orcid.org/0000-0002-9985-7746)
- Kai Chen (ORCID: https://orcid.org/0000-0002-7052-4681)
- Tingting Liu (ORCID: https://orcid.org/0000-0002-6520-2688)
- Jinfeng Chen (ORCID: https://orcid.org/0000-0002-4690-6778)
- Jue Zhang (ORCID: https://orcid.org/0000-0001-8331-2496)
- Yubin Han
- Yiming Chen (ORCID: https://orcid.org/0000-0003-1211-4366)
Institutions
- Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s12876-025-03900-4
- Citations
- 5
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 10.03
Funders
- National Natural Science Foundation of China
- Guangzhou University of Chinese Medicine
- Foshan Science and Technology Bureau
- Guangzhou University