Mendelian randomization reveals immune cell composition as a key determinant of cervical cancer prognosis

Our study utilizing the Mendelian Randomization approach provides novel insights into the causal relationships between the immune microenvironment of cervical cancer and its prognosis. The identified immune cell markers (monocyte counts, T cell ratios) have the potential to serve as prognostic biomarkers and to inform the design of targeted immunotherapeutic approaches in cervical cancer.

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Publication Details

Journal
Discover Oncology
Published
2025-04-29
DOI
https://doi.org/10.1007/s12672-025-02455-w
Citations
1
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.94
Controls
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article

Mendelian randomization reveals immune cell composition as a key determinant of cervical cancer prognosis

Yangyang Chen, Dongdong Zhong
1 citations
Discover Oncology
Cancer-related molecular mechanisms research
0.94
article

Mendelian randomization reveals immune cell composition as a key determinant of cervical cancer prognosis

Yangyang Chen, Dongdong Zhong
article en
1 citations

Abstract

Our study utilizing the Mendelian Randomization approach provides novel insights into the causal relationships between the immune microenvironment of cervical cancer and its prognosis. The identified immune cell markers (monocyte counts, T cell ratios) have the potential to serve as prognostic biomarkers and to inform the design of targeted immunotherapeutic approaches in cervical cancer.

Discover OncologyVol. 16(1)
Wenzhou City People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 26%
Cancer-related molecular mechanisms research
0.94
DOIOpen Access PDFOpenAlex
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Mendelian randomization reveals immune cell composition as a key determinant of cervical cancer prognosis — Yangyang Chen, Dongdong Zhong · Discover Oncology (2025) | TGRS Research Map | TGRS