Outcomes and predictive factors after second stereotactic radiosurgery for refractory trigeminal neuralgia
GKSRS provides effective pain relief and manageable toxicity in retreatment for refractory/recurrent TN. Optimizing parameters, including DREZ targeting and dual-isocenter strategies, can enhance outcomes, while balancing treatment length to mitigate chronic sensory toxicity. Future research should aim at optimizing treatment parameters to maximize pain relief while minimizing toxicity for these patients.
Authors
- Daniel B. Michael
- Peter Y. Chen
- James F Fontanesi
- Daniel K. Fahim (ORCID: https://orcid.org/0000-0002-2543-5778)
- Prakash Chinnaiyan (ORCID: https://orcid.org/0000-0001-9336-1734)
- Yastira Ramdas (ORCID: https://orcid.org/0000-0001-6109-0140)
- Joseph S. Lee
- Siddharth Ramanathan (ORCID: https://orcid.org/0009-0003-0239-4955)
- Bailey A. Loving (ORCID: https://orcid.org/0000-0002-2764-6122)
- Hong Ye (ORCID: https://orcid.org/0000-0003-0232-9013)
- Inga S. Grills
- J.F. Oyeniyi (ORCID: https://orcid.org/0009-0006-2217-8477)
Institutions
- Beaumont Hospital, Royal Oak (US)
- Royal Oak Community Coalition (US)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1016/j.ctro.2025.100969
- Citations
- 1
- Primary Topic
- Trigeminal Neuralgia and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.47