Metabolic Dysfunction‐Associated Steatotic Liver Disease Is Associated With Accelerated Brain Ageing: A Population‐Based Study
MASLD/related SLD, as well as MASLD and MetALD, is associated with accelerated brain ageing, even among middle-aged adults and APOE ɛ4 non-carriers. Low-grade systemic inflammation may partially mediate this association.
Authors
- Weili Xu (ORCID: https://orcid.org/0000-0001-6140-2968)
- Stéphanie Paillard‐Borg (ORCID: https://orcid.org/0000-0002-1968-2326)
- Zhong‐Ze Fang (ORCID: https://orcid.org/0000-0003-1113-9262)
- Jiao Wang (ORCID: https://orcid.org/0000-0001-6059-9279)
- Xinjie Zhang (ORCID: https://orcid.org/0009-0006-0476-1933)
- Yuyang Miao (ORCID: https://orcid.org/0000-0002-4453-9687)
- Rongrong Yang
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Sichuan University (CN)
- Röda Korsets Högskola (SE)
- Tianjin Medical University General Hospital (CN)
- Karolinska Institutet (SE)
- West China Second University Hospital of Sichuan University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Liver International
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1111/liv.70109
- Citations
- 11
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 14.90
Funders
- Forté Foundation
- National Natural Science Foundation of China
- Karolinska Institutet
- Vetenskapsrådet
- Natural Science Foundation of Chongqing
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd
- Centre Scientifique et Technique du Bâtiment