Primary Laryngeal Squamous Cell Carcinoma with DEK::AFF2 Fusion: The First Case Report

This case expands the known anatomical distribution of DEK::AFF2 fusion SCC to include the larynx, suggesting that this rare entity may arise throughout the respiratory tract epithelium. Recognition of this fusion is important in the differential diagnosis of non-keratinizing SCCs across the respiratory tract.

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Publication Details

Journal
Head and Neck Pathology
Published
2025-04-29
DOI
https://doi.org/10.1007/s12105-025-01793-z
Citations
2
Primary Topic
Tumors and Oncological Cases
Type
article
Field-Weighted Citation Impact
2.94

Funders

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article

Primary Laryngeal Squamous Cell Carcinoma with DEK::AFF2 Fusion: The First Case Report

Muh‐Hwa Yang, Ying‐Ju Kuo, Jen‐Fan Hang, Shyh‐Kuan Tai et al.
2 citations
Head and Neck Pathology
Tumors and Oncological Cases
2.94
article

Primary Laryngeal Squamous Cell Carcinoma with DEK::AFF2 Fusion: The First Case Report

Muh‐Hwa Yang, Ying‐Ju Kuo, Jen‐Fan Hang, Shyh‐Kuan Tai, Alice H. Huang
article en
2 citations

Abstract

This case expands the known anatomical distribution of DEK::AFF2 fusion SCC to include the larynx, suggesting that this rare entity may arise throughout the respiratory tract epithelium. Recognition of this fusion is important in the differential diagnosis of non-keratinizing SCCs across the respiratory tract.

Head and Neck PathologyVol. 19(1)
National Yang Ming Chiao Tung University (TW), Taipei Veterans General Hospital (TW)
Shanghai Educational Development Foundation
Good health and well-being
Openalex Percentile: Top 10%
Tumors and Oncological Cases
2.94
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