NF-κB-mediated enhancement of H3K27me3 through EZH2: a mechanism to suppress pyocyanin-induced autophagy in macrophages
The NF-κB/EZH2/H3K27me3 axis plays a pivotal role in suppressing PYO-induced autophagy in macrophages by repressing the transcription of ULK1 and MAP1LC3B.
Authors
- Y J Du (ORCID: https://orcid.org/0009-0004-1124-0832)
- Xiaowei Yi
- Simin Liang (ORCID: https://orcid.org/0009-0009-8416-6633)
- Ji Wang (ORCID: https://orcid.org/0000-0001-5871-3626)
- 敏明 渡邊 (ORCID: https://orcid.org/0009-0006-2833-6587)
Institutions
- North Sichuan Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s40001-025-02614-3
- Citations
- 2
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Natural Science Foundation of China