Cardiac substructure dose distributions in node-positive and node-negative breast cancer patients undergoing 3D-CRT: comparing the predictive accuracy of mean heart dose and mean left ventricular dose
Radiation exposure to cardiac substructures during 3D-CRT for left breast cancer was heterogeneous, with the LADCA receiving the highest mean dose, followed by the LV. MLVD demonstrated superior predictive accuracy over mean heart dose (MHD) for estimating doses to critical substructures, particularly in node-positive patients.
Authors
- Mohamad Nazrulhisham Mad Naser (ORCID: https://orcid.org/0000-0001-8498-4411)
- Noor Khairiah A. Karim (ORCID: https://orcid.org/0000-0001-8176-3939)
- Khairil Amir Sayuti (ORCID: https://orcid.org/0000-0003-1976-9568)
- Gokula Kumar Appalanaido (ORCID: https://orcid.org/0000-0002-6763-0942)
- Mohammad Gunda Nuruddeen
- Mohd Hafiz Mohd Zin
Institutions
- Universiti Sains Malaysia (MY)
- Hospital Pulau Pinang (MY)
- Hospital Universiti Sains Malaysia (MY)
- University of Maiduguri (NG)
Publication Details
- Journal
- Radiation Oncology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s13014-025-02607-w
- Citations
- 2
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.87