Association Between Epstein–Barr Virus Infection and PD-L1 Expression in Gastric Cancer: Prevalence, Clinicopathological Features, and Prognostic Implications
Our findings revealed a low prevalence of EBVaGC and PD-L1 positivity in Thailand, with no significant association or survival impact observed. These findings highlight the regional variation in these biomarkers and support EBV as an independent biomarker from PD-L1. However, further research, particularly studies evaluating immunotherapy outcomes, is warranted to clarify the predictive and clinical significance of EBV in gastric cancer.
Authors
- Jirapat Wonglhow (ORCID: https://orcid.org/0000-0003-1265-7459)
- Phatcharaporn Thongwatchara (ORCID: https://orcid.org/0000-0001-5588-8316)
- Kanet Kanjanapradit (ORCID: https://orcid.org/0000-0003-0591-0751)
- Chirawadee Sathitruangsak (ORCID: https://orcid.org/0000-0002-9788-3692)
- Arunee Dechaphunkul (ORCID: https://orcid.org/0000-0002-0593-4385)
- Patrapim Sunpaweravong (ORCID: https://orcid.org/0000-0001-9787-270X)
- Panu Wetwittayakhlang (ORCID: https://orcid.org/0000-0002-5962-4112)
- Jarukit Tantipisit (ORCID: https://orcid.org/0000-0003-2008-1699)
Institutions
- Prince of Songkla University (TH)
Publication Details
- Journal
- Cancers
- Published
- 2025-04-29
- DOI
- https://doi.org/10.3390/cancers17091492
- Citations
- 2
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Prince of Songkla University
- Faculty of Medicine, Prince of Songkla University