Calcitonin gene-related peptide in newly diagnosed idiopathic intracranial hypertension: a prospective, cross-sectional, case-control study of cerebrospinal fluid and plasma
CGRP levels in plasma and CSF and their ratios were comparable in IIH, non-IIH patients with headache, and sex-, age-, and BMI-matched HC. CGRP in plasma correlated with CGRP in CSF. Due to methodology, we probably measured basal resting CGRP. The role of CGRP in IIH-headache needs further clarification. A headache preventive effect in IIH of anti-CGRP targeted therapy remains a relevant unexplored area.
Authors
- Dagmar Beier (ORCID: https://orcid.org/0000-0002-3336-157X)
- Johanne Juhl Korsbæk (ORCID: https://orcid.org/0000-0002-5730-0712)
- Rigmor Jensen (ORCID: https://orcid.org/0000-0001-6433-5887)
- Lasse K. Bak (ORCID: https://orcid.org/0000-0003-0784-7864)
- Nadja Skadkær Hansen (ORCID: https://orcid.org/0000-0002-5488-7992)
- Niklas Rye Jørgensen (ORCID: https://orcid.org/0000-0001-9624-5210)
Institutions
- University of Copenhagen (DK)
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
- Glostrup Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- The Journal of Headache and Pain
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s10194-025-02042-y
- Citations
- 4
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.88
Funders
- Københavns Universitet