Untargeted metabolomics analysis of the spleens of ducks infected with Clostridium perfringens type A

These findings suggest that C. perfringens type A infection causes a duck spleen inflammatory response and immune response in infected ducks through indolin-2-one, 3-methylindole, 4-hydroxy-2-quinolinecarboxylic acid and tryptophan metabolism, purine metabolism, nicotinic acid and nicotinamide metabolism, which provides a basis for understanding the pathogenesis of C. perfringens type A in ducks.

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Publication Details

Journal
BMC Veterinary Research
Published
2025-04-29
DOI
https://doi.org/10.1186/s12917-025-04539-9
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
Field-Weighted Citation Impact
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article

Untargeted metabolomics analysis of the spleens of ducks infected with Clostridium perfringens type A

Chunyin Zeng, Ying Yang, Na Wang, Ming Wen et al.
BMC Veterinary Research
Clostridium difficile and Clostridium perfringens research
article

Untargeted metabolomics analysis of the spleens of ducks infected with Clostridium perfringens type A

Chunyin Zeng, Ying Yang, Na Wang, Ming Wen, Zhou BiJun
article en

Abstract

These findings suggest that C. perfringens type A infection causes a duck spleen inflammatory response and immune response in infected ducks through indolin-2-one, 3-methylindole, 4-hydroxy-2-quinolinecarboxylic acid and tryptophan metabolism, purine metabolism, nicotinic acid and nicotinamide metabolism, which provides a basis for understanding the pathogenesis of C. perfringens type A in ducks.

BMC Veterinary ResearchVol. 21(1)
Guizhou University (CN), China Animal Disease Control Center (CN)
Zero hunger
Openalex Percentile: Top 88%
Clostridium difficile and Clostridium perfringens research
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