Study shows improved schizophrenia negative symptoms with xanomeline‐trospium

depression, interpersonal sensitivity, hostility, obsession-compulsion, and somatization.Psilocybin-assisted therapy also did not induce lasting paranoia, phobia, or psychosis, with the study's authors writing that these findings add "further evidence that psilocybin can be safely administered following rigorous screening under close medical supervision." The researchers attributed the multidimensional effects of psilocybin in part to its action on the serotonin 2A receptor."While larger clinical trials will ultimately be needed to validate these findings, our study suggests that [psilocybin-assisted psychotherapy] has the potential to be a comprehensive mental health treatment for patients with cancer, " the authors wrote.[

Publication Details

Journal
The Brown University Psychopharmacology Update
Published
2025-04-29
DOI
https://doi.org/10.1002/pu.31318
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
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article

Study shows improved schizophrenia negative symptoms with xanomeline‐trospium

The Brown University Psychopharmacology Update
Schizophrenia research and treatment
article

Study shows improved schizophrenia negative symptoms with xanomeline‐trospium

article en

Abstract

depression, interpersonal sensitivity, hostility, obsession-compulsion, and somatization.Psilocybin-assisted therapy also did not induce lasting paranoia, phobia, or psychosis, with the study's authors writing that these findings add "further evidence that psilocybin can be safely administered following rigorous screening under close medical supervision." The researchers attributed the multidimensional effects of psilocybin in part to its action on the serotonin 2A receptor."While larger clinical trials will ultimately be needed to validate these findings, our study suggests that [psilocybin-assisted psychotherapy] has the potential to be a comprehensive mental health treatment for patients with cancer, " the authors wrote.[

The Brown University Psychopharmacology UpdateVol. 36(6)
Openalex Percentile: Top 89%
Schizophrenia research and treatment
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Study shows improved schizophrenia negative symptoms with xanomeline‐trospium · The Brown University Psychopharmacology Update (2025) | TGRS Research Map | TGRS