Changes in blood pressure, medication adherence, and cardiovascular-related health care use associated with the 2018 angiotensin receptor blocker recalls and drug shortages among patients with hypertension
The 2018 ARB recalls were associated with immediate changes in antihypertension medication use. Many patients transitioned to alternative medications. Although overall impacts on clinical outcomes were minimal and not statistically significant, small increases in medication gaps and MACE-related acute care visits among some patients occurred after more than 1 year. The ARB recalls may have been associated with fewer adverse events than other recent shortages owing to the widespread availability of alternative treatments in the same or similar drug class.
Authors
- Eric T. Roberts (ORCID: https://orcid.org/0000-0002-7439-0799)
- Katie J. Suda
- Chester B. Good (ORCID: https://orcid.org/0000-0003-4388-4558)
- Mina Tadrous (ORCID: https://orcid.org/0000-0003-1911-6129)
- Julie M. Donohue
- Lindsay M. Sabik (ORCID: https://orcid.org/0000-0002-0613-4929)
- Joshua W. Devine (ORCID: https://orcid.org/0009-0004-1508-3846)
- Katherine Callaway Kim (ORCID: https://orcid.org/0000-0002-2924-6165)
Institutions
- University of Pittsburgh (US)
- University of Toronto (CA)
- Women's College Hospital (CA)
- VA Pittsburgh Healthcare System (US)
- University of Pittsburgh Medical Center (US)
- UPMC Center for High Value Health Care (US)
- University of Pennsylvania (US)
- Des Moines University (US)
Publication Details
- Journal
- Journal of Managed Care & Specialty Pharmacy
- Published
- 2025-04-29
- DOI
- https://doi.org/10.18553/jmcp.2025.31.5.461
- Citations
- 2
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.78