Evaluating Adjuvant Radiation Therapy for Grade 2 Meningioma: A Multi-Institutional Analysis
Adjuvant RT for grade 2 meningioma may reduce tumor progression for patients with Ki67 index ≥10% or after STR and should be considered as part of a multidisciplinary approach to postoperative management. Routine use of adjuvant RT after GTR was not associated with improved PFS, for which avoidance of RT after GTR should be considered to minimize potential treatment-associated morbidity. This study supports selective use of adjuvant RT, optimizing patient outcomes by balancing the benefits of reduced progression against potential morbidities of treatment.
Authors
- Shyam Kumar Tanguturi (ORCID: https://orcid.org/0000-0001-6479-1946)
- Joshua D. Bernstock (ORCID: https://orcid.org/0000-0002-7814-3867)
- Velina S. Chavarro (ORCID: https://orcid.org/0000-0002-5925-2937)
- Saksham Gupta (ORCID: https://orcid.org/0000-0002-7538-6345)
- Timothy R. Smith (ORCID: https://orcid.org/0000-0003-1976-0766)
- Omar Arnaout (ORCID: https://orcid.org/0000-0003-3890-8615)
- Harshit Arora (ORCID: https://orcid.org/0000-0003-0329-6903)
- Lila Medeiros
- Rayha Karanth
- Samantha Sadler (ORCID: https://orcid.org/0000-0002-6939-7953)
- Marcelle Altshuler (ORCID: https://orcid.org/0000-0003-4304-7207)
- Brian V. Nahed (ORCID: https://orcid.org/0000-0001-8537-106X)
- Neel H. Mehta (ORCID: https://orcid.org/0000-0002-5144-4635)
- Noah Nawabi
- Rohan Jha
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Medical University of South Carolina (US)
- University of Washington (US)
- Massachusetts General Hospital (US)
- Mass General Brigham (US)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1227/neu.0000000000003469
- Citations
- 2
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 2.71