CLINICAL CASE REPORT: RECONSTRUCTION OF A LARGE MAXILLOFACIAL DEFECT USING AN ANTEROLATERAL THIGH FREE FLAP AFTER NEUROFIBROMA RESECTION

Objective: To describe the clinical and paraclinical characteristics of large neurofibromas in the maxillofacial region and propose an effective treatment approach for patients. Clinical case: A 53-year-old female patient presented with a progressively enlarging tumor on the left side of her face. She had a history of undergoing partial tumor resection at the age of 14. Upon examination, the tumor had infiltrated and caused deformities in the left temporal region, orbit, cheek, and scalp. Histopathological findings confirmed plexiform neurofibroma. The patient underwent near-total tumor resection, followed by reconstruction using an anterolateral thigh free flap. Postoperatively, the patient received proactive blood transfusions, and no complications occurred. Immediate postoperative and long-term follow-up at one year demonstrated that the flap successfully covered the extensive defect while achieving satisfactory functional and aesthetic outcomes. Conclusion: Large neurofibromas in the craniofacial region cause significant facial deformities and impact both function and aesthetics. Proper preoperative planning and the selection of an appropriate reconstructive technique can ensure surgical safety and provide satisfactory aesthetic and functional restoration.