Identifying Metabolomic Biomarkers of Lung Function Decline in People with HIV
Baseline metabolomic profiling, especially using BALF, can help identify PWH at risk for accelerated lung function decline. Key metabolic pathways related to glucose oxidation, fatty acid metabolism, and amino acid metabolism underlie observed lung function changes.
Authors
- Charles R. Rinaldo (ORCID: https://orcid.org/0000-0002-9194-3164)
- Stephen Y. Chan (ORCID: https://orcid.org/0000-0002-9520-7527)
- Panayiotis V. Benos (ORCID: https://orcid.org/0000-0003-3172-3132)
- Stacy G. Wendell (ORCID: https://orcid.org/0000-0001-9083-6933)
- Biying Zhang
- Shulin Qin (ORCID: https://orcid.org/0000-0003-2496-3007)
- Tyler Lovelace (ORCID: https://orcid.org/0000-0002-7881-9054)
- Cathy Murray (ORCID: https://orcid.org/0000-0003-0532-0129)
- Barbara A. Methé (ORCID: https://orcid.org/0000-0001-8711-1448)
- Heather Gentry
- Kelvin Li (ORCID: https://orcid.org/0000-0003-3922-5664)
- Alison Morris
- Steven J. Mullett (ORCID: https://orcid.org/0009-0005-6971-9288)
Institutions
- University of Pittsburgh (US)
- University of Florida (US)
Publication Details
- Journal
- JAIDS Journal of Acquired Immune Deficiency Syndromes
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1097/qai.0000000000003689
- Primary Topic
- Pneumocystis jirovecii pneumonia detection and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00