The Role of Presepsin in Differentiating Between Bacterial and Viral Infections in Young Infants With Fever of Unknown Origin on the Emergency Department
Presepsin has limited discriminative value between bacterial and viral infections in young infants at the emergency department, because the majority of bacterial infections concern a urinary tract infection, in which plasma presepsin was not elevated. The diagnostic accuracy of presepsin for sepsis in this population could not be established due to a low incidence of sepsis cases.
Authors
- Dorine Borensztajn (ORCID: https://orcid.org/0000-0002-2437-0757)
- Douwe H. Visser (ORCID: https://orcid.org/0009-0001-9767-0339)
- Sjoerd C. J. Nagelkerke (ORCID: https://orcid.org/0000-0001-6337-7348)
- Jeroen Hol (ORCID: https://orcid.org/0000-0003-4481-7250)
- Charlotte M. Nusman (ORCID: https://orcid.org/0000-0002-7923-1690)
- Frans B. Plötz (ORCID: https://orcid.org/0000-0003-0858-3119)
- Maya W. Keuning (ORCID: https://orcid.org/0000-0003-3478-5339)
- Sarah M. Schouten
Institutions
- Noordwest Ziekenhuisgroep (NL)
- Emma Kinderziekenhuis (NL)
- Tergooi (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1097/inf.0000000000004837
- Citations
- 1
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.88