Energy and Resource Efficient Continuous Cooling Crystallization with Modular Lab-Scale Equipment

Small-scale modular apparatuses in continuously operated plants are promising for current and future production processes in fine and specialty chemistry. Different lab-scale crystallizers have been developed and characterized as part of the ENPRO-TeiA project—separation processes with efficient and intelligent apparatuses. Two research groups at TU Dortmund University have investigated four miniaturized crystallization apparatuses for cooling crystallization and characterized them for scaling up to pilot scale with industrial partners. The use in an industrial environment was successfully demonstrated for two types of crystallizers: the stirred tank cascade as well as a draft tube baffle crystallizer. The ENPRO-TeiA project was thus able to prototypically demonstrate the manufacturer-independent investigation and scaling of modular systems for the crystallization step, which is an essential cornerstone for the process development acceleration for sustainable production in the pharmaceutical and chemical industries.