Clinical correlation and survival analysis of hepatitis B virus infection in oral squamous cell carcinoma: a retrospective study of 1373 patients
HBsAg is a potential prognostic marker for OSCC. It is essential to screen for HBV infection prior to initiating tumor treatment. Additionally, serological testing, antiviral prophylaxis and therapy play crucial roles in preventing HBV reactivation during the course of tumor treatment. In cases of early OSCC associated with HBV infection, elective neck dissection has been shown to reduce the rates of recurrence and metastasis significantly.
Authors
- Rukeng Tan
- Zengyu Chen (ORCID: https://orcid.org/0009-0008-1196-0468)
- Yiyao Zhu
- Sien Zhang (ORCID: https://orcid.org/0000-0002-8233-6098)
- Guiqing Liao (ORCID: https://orcid.org/0009-0001-9411-1443)
- Xinkai Feng
- Yujie Liang
- Le Yang
- Nuerbiya Abuduxiku
Institutions
- Sun Yat-sen University (CN)
- Key Laboratory of Guangdong Province (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Stomatology Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s12885-025-14188-8
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chinese Stomatological Association