Conjunctival MicroRNA Expression Signature in Primary Sjögren's Syndrome Dry Eye: A NanoString-Based Bioinformatic Analysis
This study underscores the potential of miRNAs as biomarkers and therapeutic targets in pSS-associated dry eye disease. Despite limitations like small sample size and reliance on in silico predictions, our findings provide valuable insights into miRNA-mediated regulation of immune responses and inflammation, paving the way for future diagnostic and therapeutic advancements.
Authors
- Ludovico Alisi (ORCID: https://orcid.org/0000-0001-5366-882X)
- Francesca Giovannetti (ORCID: https://orcid.org/0000-0002-7661-6675)
- Marta Armentano (ORCID: https://orcid.org/0009-0005-3414-6344)
- Francesca Megiorni (ORCID: https://orcid.org/0000-0003-3705-3248)
- Paola Pontecorvi (ORCID: https://orcid.org/0000-0003-2392-3775)
- Alice Bruscolini (ORCID: https://orcid.org/0000-0002-1627-5493)
- Cinzia Marchese (ORCID: https://orcid.org/0000-0002-9280-8917)
- Alessandro Lambìase (ORCID: https://orcid.org/0000-0002-8974-991X)
- Enrico Romano (ORCID: https://orcid.org/0000-0003-4276-8432)
Institutions
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1167/iovs.66.4.80
- Citations
- 3
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 3.49