Clinicopathological characterization of Switch/Sucrose-non-fermentable (Swi/Snf) complex (ARID1A, SMARCA2, SMARCA4)-deficient endocervical adenocarcinoma
Swi/Snf complex deficiency is rare but significantly associated with NHPVA, aggressive pathological features, immunologically activated phenotypes, and MMRD. Swi/Snf status evaluation may inform novel therapeutic strategies for ECA patients.
Authors
- Lijun Wei (ORCID: https://orcid.org/0000-0002-5685-4940)
- Rongzhen Luo (ORCID: https://orcid.org/0000-0002-6599-0370)
- Xia Yang (ORCID: https://orcid.org/0000-0003-2361-6003)
- Chao Cao
- Lili Liu (ORCID: https://orcid.org/0000-0002-4347-2038)
- Wei Liao (ORCID: https://orcid.org/0000-0002-7945-6726)
- Wu Zz
- Haoyu Liang
Institutions
- Sun Yat-sen University (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s12935-025-03794-y
- Primary Topic
- Chromatin Remodeling and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00