Postoperative leukopenia after cytoreductive surgery and hypertherm intraperitoneal chemotherapy for colorectal carcinomatosis– causes and implication on outcomes in a population-based study

Postoperative leukopenia did not impact recurrence rate or long-term survival in a statistically significant manner. Neoadjuvant chemotherapy and high PCI-score were associated with both recurrent disease and mortality within 3 years.

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Publication Details

Journal
World Journal of Surgical Oncology
Published
2025-04-29
DOI
https://doi.org/10.1186/s12957-025-03821-2
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Postoperative leukopenia after cytoreductive surgery and hypertherm intraperitoneal chemotherapy for colorectal carcinomatosis– causes and implication on outcomes in a population-based study

Per J. Nilsson, Valentinus Valdimarsson, Peter Cashin, Nader Algethami et al.
3 links
World Journal of Surgical Oncology
Intraperitoneal and Appendiceal Malignancies
article

Postoperative leukopenia after cytoreductive surgery and hypertherm intraperitoneal chemotherapy for colorectal carcinomatosis– causes and implication on outcomes in a population-based study

Per J. Nilsson, Valentinus Valdimarsson, Peter Cashin, Nader Algethami, Lana Ghanipour, Ingvar Syk, Gabriella Jansson Palmer, Elinor Bexe Lindskog, Mattias Lepsenyi, Henrik Thorlacius, Dan Asplund
article en

Abstract

Postoperative leukopenia did not impact recurrence rate or long-term survival in a statistically significant manner. Neoadjuvant chemotherapy and high PCI-score were associated with both recurrent disease and mortality within 3 years.

World Journal of Surgical OncologyVol. 23(1)
Karolinska University Hospital (SE), Uppsala University Hospital (SE), Malmö University (SE), Sahlgrenska University Hospital (SE), Karolinska Institutet (SE), Skåne University Hospital (SE), University of Gothenburg (SE)
Good health and well-being
Openalex Percentile: Top 84%
Intraperitoneal and Appendiceal Malignancies
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Postoperative leukopenia after cytoreductive surgery and hypertherm intraperitoneal chemotherapy for colorectal carcinomatosis– causes and implication on outcomes in a population-based study — Per J. Nilsson, Valentinus Valdimarsson, et al. · World Journal of Surgical Oncology (2025) | TGRS Research Map | TGRS