Analysis of extraocular muscle volumes in idiopathic hypertrophic pachymeningitis patients

In idiopathic HP patients, significantly larger EOM volumes were found compared to control subjects. This enlargement could be due to the diffuse infiltrative histopathology potentially involving microstructures in the EOM. Extraocular movement limitations may be related to cranial nerve involvement. However, the enlarged EOM volumes show no significant correlation with extraocular movement limitation.

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Journal
PLoS ONE
Published
2025-04-29
DOI
https://doi.org/10.1371/journal.pone.0309638
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
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Analysis of extraocular muscle volumes in idiopathic hypertrophic pachymeningitis patients

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Analysis of extraocular muscle volumes in idiopathic hypertrophic pachymeningitis patients

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article en

Abstract

In idiopathic HP patients, significantly larger EOM volumes were found compared to control subjects. This enlargement could be due to the diffuse infiltrative histopathology potentially involving microstructures in the EOM. Extraocular movement limitations may be related to cranial nerve involvement. However, the enlarged EOM volumes show no significant correlation with extraocular movement limitation.

PLoS ONEVol. 20(4)
Siriraj Hospital (TH), Mahidol University (TH)
Good health and well-being
Openalex Percentile: Top 86%
IgG4-Related and Inflammatory Diseases
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