<scp>FIGO</scp> guideline on liver disease and pregnancy

The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management. This FIGO (the International Federation of Gynecology & Obstetrics) guideline aims to use the latest evidence to inform practice relevant to a global population. The immediate past and present chairs of FIGO's Committee on the Impact of Pregnancy on Long-term Health invited the Chair of the European guideline, alongside two trainees with an interest in liver disorders in pregnancy, to develop a guideline relevant to a global audience, thus serving the real-world population and fulfilling FIGO's ambition to enhance their global voice for women's health. Experts in the field with experience in managing liver disorders in pregnancy from a diverse selection of continents helped to develop a guideline. The guideline includes the most common pre-existing and gestational liver disorders. Evidence-based best practice recommendations are summarized in addition to pragmatic recommendations. Printable tables/figures are included in the guideline for ease of use. These include a table of normal ranges of commonly used blood tests, a table outlining safety of investigations, and a table of delivery considerations relevant to a global audience. Figures designed to summarize each section of the guideline and the multidisciplinary approach to managing liver disorders in pregnancy are also included. This guideline incorporates guidance for a global audience aimed at improving the management of women with pre-existing and new liver disease in pregnancy.

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Publication Details

Journal
International Journal of Gynecology & Obstetrics
Published
2025-04-29
DOI
https://doi.org/10.1002/ijgo.70161
Citations
7
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
9.25
Controls
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article

FIGO guideline on liver disease and pregnancy

Ciara McCormick, Melanie Nana, Liona C. Poon, Sharleen O’Reilly et al.
7 citations
International Journal of Gynecology & Obstetrics
Liver Disease and Transplantation
9.25
article

FIGO guideline on liver disease and pregnancy

Ciara McCormick, Melanie Nana, Liona C. Poon, Sharleen O’Reilly, Titus Beyuo, Ulrich H. Beuers, Sumaiya Adam, Virna P. Medina, Francisco Ruiloba, Anil Kapur, Graeme N. Smith, Claudio Sosa, Mary Rosser, Lina Bergman, Fionnuala Mary McAuliffe, Catherine Williamson, Valerie T. Guinto, Gloria Taliani, Cynthia Maxwell, Patrick O’Brien, Bo Jacobsson, Mark A. Hanson, Deborah Money
article en
7 citations

Abstract

The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management. This FIGO (the International Federation of Gynecology & Obstetrics) guideline aims to use the latest evidence to inform practice relevant to a global population. The immediate past and present chairs of FIGO's Committee on the Impact of Pregnancy on Long-term Health invited the Chair of the European guideline, alongside two trainees with an interest in liver disorders in pregnancy, to develop a guideline relevant to a global audience, thus serving the real-world population and fulfilling FIGO's ambition to enhance their global voice for women's health. Experts in the field with experience in managing liver disorders in pregnancy from a diverse selection of continents helped to develop a guideline. The guideline includes the most common pre-existing and gestational liver disorders. Evidence-based best practice recommendations are summarized in addition to pragmatic recommendations. Printable tables/figures are included in the guideline for ease of use. These include a table of normal ranges of commonly used blood tests, a table outlining safety of investigations, and a table of delivery considerations relevant to a global audience. Figures designed to summarize each section of the guideline and the multidisciplinary approach to managing liver disorders in pregnancy are also included. This guideline incorporates guidance for a global audience aimed at improving the management of women with pre-existing and new liver disease in pregnancy.

International Journal of Gynecology & ObstetricsVol. 170(1)
University College Dublin (IE), University of Ghana (GH), University of British Columbia (CA), Chinese University of Hong Kong (HK), Universidad de la República de Uruguay (UY), King's College London (GB), Queen's University (CA), Columbia University Irving Medical Center (US), Centro Hospitalario Pereira Rossell (UY), Sahlgrenska University Hospital (SE), Women's College Hospital (CA), Philippine General Hospital (PH), University Hospital Southampton NHS Foundation Trust (GB), World Diabetes Foundation (DK), Instituto Nacional de Perinatología (MX), London Women's Clinic (GB), Prince of Wales Hospital (CN), National Maternity Hospital (IE), Amsterdam University Medical Centers (NL), Kingston Health Sciences Centre (CA), University College London (GB), Imperial College London (GB), University of Pretoria (ZA), Sapienza University of Rome (IT), University of Gothenburg (SE), Universidad del Valle (CO)
Good health and well-being
Openalex Percentile: Top 2%
Liver Disease and Transplantation
9.25
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