Evaluation of a simplified radiolabeling method for a PARP inhibitor in an animal model of breast cancer
This suggests that the I-123/125-KX1 prepared using the SPE method showed some comparable properties to those from the traditional method, indicating its potential suitability for future radioligand preparation in PARP studies. However, further characterization studies may be needed to confirm its efficacy.
Authors
- Ing‐Tsung Hsiao (ORCID: https://orcid.org/0000-0002-5255-7498)
- Chi-Chang Weng (ORCID: https://orcid.org/0000-0002-2989-3303)
- Robert H. Mach (ORCID: https://orcid.org/0000-0002-7645-2869)
- Yi‐Hsiu Chung (ORCID: https://orcid.org/0000-0001-5308-2554)
- Chao-Chih Chiang
- Yu-Chuan Chang (ORCID: https://orcid.org/0000-0002-0001-3624)
- Yi-Pei Ho
Institutions
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- University of Pennsylvania (US)
Publication Details
- Journal
- EJNMMI Research
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1186/s13550-025-01236-4
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chang Gung Memorial Hospital
- National Science Council
- Chang Gung University
- Chang Gung Medical Foundation
- Chang Gung Memorial Hospital, Linkou
- National Science and Technology Council
- Healthy Aging Research Center