A new alkaloid and five known compounds from <i>Portulaca oleracea</i> L. and their anti-inflammatory activities

A new alkaloid, identified (<i>R</i>,<i>Z</i>)-2-hydroxy-8-(4-hydroxyphenyl)-4,5-diimino-4,5-dihydro-9<i>H</i>-1,3,6-trioxonin-9-one, named oleracimine C (<b>1</b>), together with five known compounds, 4-hydroxybenzaldehyde (<b>2</b>), 2-piperidone (<b>3</b>), thymidine (<b>4</b>), 5-hydroxypicolinic acid (<b>5</b>), 7-hydroxy-3-(4-hydroxyphenyl)-4<i>H</i>-chromen-4-one (<b>6</b>), were successfully derived from <i>Portulaca oleracea</i> L. The structures of the compounds were successfully elucidated <i>via</i> NMR, CD, and UHPLC-ESI-Q-TOF/MS methods. Furthermore, the findings indicated that compounds <b>1</b>, <b>3</b>, <b>4</b> can possess the ability to suppress the release of nitric oxide, an inflammatory factor, and demonstrate substantial anti-inflammatory effects.