Clinical Implications of The Cancer Genome Atlas Molecular Classification System in Esophagogastric Cancer
Molecular classification is independently prognostic and may warrant inclusion in future staging and treatment guidelines. Routine molecular profiling is clinically feasible and may play a role in the management of patients to help guide appropriate treatment selection and clinical trial enrollment in the place of tumor location.
Authors
- Daniela Molena (ORCID: https://orcid.org/0000-0003-1655-4473)
- Henry S. Walch (ORCID: https://orcid.org/0000-0003-1188-350X)
- Yelena Y. Janjigian (ORCID: https://orcid.org/0000-0002-5357-5858)
- Walid K. Chatila (ORCID: https://orcid.org/0000-0001-5474-218X)
- Daniel G. Coit (ORCID: https://orcid.org/0000-0001-8901-1555)
- Abraham J. Wu (ORCID: https://orcid.org/0000-0002-2597-7091)
- Bernard J. Park (ORCID: https://orcid.org/0000-0003-3814-5144)
- Nikolaus Schultz (ORCID: https://orcid.org/0000-0002-0131-4904)
- Matthew Joseph Bott (ORCID: https://orcid.org/0000-0003-0523-4028)
- David H. Ilson (ORCID: https://orcid.org/0000-0003-0831-2247)
- Michael F. Berger (ORCID: https://orcid.org/0000-0003-3882-5000)
- Vivian E. Strong (ORCID: https://orcid.org/0000-0001-5044-1662)
- Katherine D. Gray (ORCID: https://orcid.org/0000-0002-6512-8406)
- Steven B. Maron (ORCID: https://orcid.org/0000-0002-8794-130X)
- Valerie W. Rusch (ORCID: https://orcid.org/0000-0003-2345-6900)
- Justin Jee (ORCID: https://orcid.org/0000-0001-9783-0139)
- David R. Jones (ORCID: https://orcid.org/0000-0002-3318-0146)
- Geoffrey Y. Ku (ORCID: https://orcid.org/0000-0002-0448-1038)
- Manjit S. Bains (ORCID: https://orcid.org/0009-0001-5406-0784)
- Smita Sihag (ORCID: https://orcid.org/0000-0002-5041-3941)
- Christopher Fong (ORCID: https://orcid.org/0000-0002-8929-1478)
- Pari Shah (ORCID: https://orcid.org/0000-0002-9846-3729)
- Raktim Borpatragohain
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-3473
- Citations
- 4
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.03
Funders
- U.S. Department of Defense
- National Cancer Institute