The incremental value of tuberculosis detecting African giant pouched rats over Smear microscopy and Xpert MTB/RIF for Tanzanian TB detection
Our finding indicated that trained rats reasonably added benefit over DOT TB case findings. According to our data, switching from smear to Xpert sites lowered the added value by more than a quarter, even though the Xpert sites were likely to benefit more case finding among TB patients with lower bacillary loads.
Authors
- Cynthia D. Fast (ORCID: https://orcid.org/0000-0002-3764-565X)
- Stephen Mwimanzi
- Negussie Beyene (ORCID: https://orcid.org/0000-0003-0529-6667)
- Christophe Cox (ORCID: https://orcid.org/0009-0009-3118-4491)
- Gilbert Mwesiga
- Joseph Soka
- Tefera Agizew (ORCID: https://orcid.org/0000-0003-1848-7307)
- Marygiven Stephen
- N Edward
- Rehema Kondo
Institutions
- University of Antwerp (BE)
- Armauer Hansen Research Institute (ET)
- Sokoine University of Agriculture (TZ)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1371/journal.pone.0321866
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Else Kröner-Fresenius-Stiftung