Allergic Fungal Rhinosinusitis and Eosinophilic Chronic Rhinosinusitis Have Different Phenotypes in Japan
AFRS exhibits unique clinical features compared with eCRS. Cluster analysis identified three distinct AFRS phenotypes characterized by CT findings, eosinophilic inflammation, and specific IgE levels against inhaled antigens. These findings underscore the importance of differential diagnosis and personalized treatment strategies for AFRS and eCRS.
Authors
- Mamoru Yoshikawa (ORCID: https://orcid.org/0000-0002-5908-1752)
- Yoshinori Matsuwaki (ORCID: https://orcid.org/0000-0002-9089-2174)
- Takashi Kashiwagi
- Natsuki Inoue (ORCID: https://orcid.org/0000-0002-6794-3885)
- Makoto Akutsu (ORCID: https://orcid.org/0000-0003-4365-6731)
- Tsuguhisa Nakayama (ORCID: https://orcid.org/0000-0001-8761-9292)
- Yasuhiro Tsunemi
Institutions
- Toho University (JP)
- Toho University Ohashi Medical Center (JP)
- Dokkyo Medical University (JP)
Publication Details
- Journal
- International Forum of Allergy & Rhinology
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1002/alr.23597
- Citations
- 1
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 1.85