DERL3 facilitates the progression of clear cell renal cell carcinoma by promoting epithelial-mesenchymal transition via regulation of the TGFB1 pathway
In conclusion, our study clarifies the role and potential mechanisms of DERL3 in ccRCC progression, providing promising therapeutic avenues for improving the prognosis of ccRCC patients.
Authors
- Xintong Sun
- Yuchang Yang (ORCID: https://orcid.org/0000-0002-4603-9790)
- Zhihong Niu (ORCID: https://orcid.org/0000-0003-2840-0981)
- Wei He (ORCID: https://orcid.org/0000-0002-4272-2891)
- Yiming Zhang (ORCID: https://orcid.org/0000-0001-8547-6654)
- Hong Cui
- Chengtao Niu (ORCID: https://orcid.org/0000-0002-5218-7511)
- Zixiang Cong
- Xue Jiang (ORCID: https://orcid.org/0009-0001-3790-5757)
Institutions
- Shandong University (CN)
- Shandong Xiehe University (CN)
- Shandong Provincial Hospital (CN)
- Weihai Municipal Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1371/journal.pone.0322172
- Citations
- 1
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Natural Science Foundation of Shandong Province
- Postdoctoral Innovation Project of Shandong Province
- Youth Innovation Technology Project of Higher School in Shandong Province